Integrative effects of Telomere Length, Epigenetic Age, and Mitochondrial DNA abundance in Alzheimer's Disease
Shea J. Andrews, Rakshya U Sharma, Brendan A. Mitchell, Tong Tong, Luke W. Bonham, Alan Edward Renton, Xiaoling Zhang, Marina Sirota, Duygu Tosun, Kristine S. Yaffe, the Alzheimer’s Disease Neuroimaging Initiative
This study examines how telomere length, epigenetic age, and mitochondrial DNA abundance interact in Alzheimer's Disease, finding that their combination affects grey-matter volume.
medRxiv · Jul 16, 2025 · PreprintGenetic & Genomic Medicine