Author

Rakshya U Sharma

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Shea J. AndrewsiD· 2 shared Aadrita ChatterjeeiD· 1 shared Alan Edward RentoniD· 1 shared Alison GoateiD· 1 shared Brendan A. Mitchell· 1 shared Brian D Alvarez· 1 shared Caroline JonsoniD· 1 shared Duygu TosuniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Shea J. AndrewsORCID

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2 papers

Recent·Most cited

Evaluating the causal effect of mitochondrial dysfunction on Alzheimer's and Parkinson's disease using Polygenic Risk Scores and Mendelian Randomization

Aadrita Chatterjee, Brian D Alvarez, Rakshya U Sharma, Caroline Jonson, Heather M. Wilkins, Judy Pa, Russell Howard Swerdlow, Alison Goate, Kristine Yaffe, Shea J. Andrews

This paper uses Polygenic Risk Scores and Mendelian Randomization to evaluate the causal effect of mitochondrial DNA copy number on Alzheimer's and Parkinson's disease risk.

Alzheimer s & Dementia · Dec 1, 2025Peer-reviewedGenetic & Genomic Medicine

Integrative effects of Telomere Length, Epigenetic Age, and Mitochondrial DNA abundance in Alzheimer's Disease

Shea J. Andrews, Rakshya U Sharma, Brendan A. Mitchell, Tong Tong, Luke W. Bonham, Alan Edward Renton, Xiaoling Zhang, Marina Sirota, Duygu Tosun, Kristine S. Yaffe, the Alzheimer’s Disease Neuroimaging Initiative

This study examines how telomere length, epigenetic age, and mitochondrial DNA abundance interact in Alzheimer's Disease, finding that their combination affects grey-matter volume.

medRxiv · Jul 16, 2025 · PreprintGenetic & Genomic Medicine