Mechanochemical cues control the coupling of metabolic and migratory patterns in cancer
Alice Amitrano, Debanik Choudhury, Brent Ifemembi, Alexandros Afthinos, Konstantin V. Stoletov, Qinling Yuan, Sanjiban Nath, Bishwa Ranjan Si, Bhawana Agarwal, Gianna Graziano, Jack Gao, Anneliese Ceisel, Matthew Hauf, Sean X. Sun, Andrew J. Ewald, , Κωνσταντίνος Κωνσταντόπουλος
The paper shows that cancer cells switch between glycolysis and oxidative phosphorylation based on microenvironment stiffness, affecting their migration patterns.
bioRxiv · Aug 24, 2026 · PreprintCell Biology