Author

Bret Holt

Gladstone Institutes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alina L Chadarevian· 1 shared Alissa L. NanaiD· 1 shared Ani Agababian· 1 shared Claire Dudley ClellandiD· 1 shared Eric Jinsheng HuangiD· 1 shared Ghazaleh Eskandari‐SedighiiD· 1 shared Hayk DavtyaniD· 1 shared J.L. Giacchino· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alina L Chadarevian

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Transplantation of Human IPSC-derived Microglia Ameliorates Neuropathology and Circuit Dysfunction in Progranulin-Deficient Mice

Hayk Davtyan, Sarah A. Naguib, Yuliya Voskobiynyk, Jean Paul Chadarevian, Joia Kai Capocchi, J.L. Giacchino, Ghazaleh Eskandari‐Sedighi, Vivianna R. DeNittis, Jeremy B. Ford, Ani Agababian, Jasmine Nguyen, Alina L Chadarevian, Madison S. Sutherland, Sepideh Kiani Shabestari, Kayla Nhi Tran, , Li Gan

This study shows that transplanting wild-type human iPSC-derived microglia into progranulin-deficient mice reduces neuropathology, circuit dysfunction, and behavioral issues in a FTD model.

Molecular Neurodegeneration · Jul 16, 2026Peer-reviewedNeuroscience