Author

Vivianna R. DeNittis

Gladstone InstitutesORCID 0009-0004-8485-6590Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Jeanne T. PaziD· 2 shared Alina L Chadarevian· 1 shared Alissa L. NanaiD· 1 shared Ani Agababian· 1 shared Bret Holt· 1 shared Claire Dudley ClellandiD· 1 shared Eric Jinsheng HuangiD· 1 shared Ghazaleh Eskandari‐SedighiiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Jeanne T. PazORCID

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2 papers

Recent·Most cited

NeuroscienceMolecular NeurodegenerationPeer-reviewedJul 16, 2026

Transplantation of Human IPSC-derived Microglia Ameliorates Neuropathology and Circuit Dysfunction in Progranulin-Deficient Mice

Hayk Davtyan, Sarah A. Naguib, Yuliya Voskobiynyk…·Li Gan

This study shows that transplanting wild-type human iPSC-derived microglia into progranulin-deficient mice reduces neuropathology, circuit dysfunction, and behavioral issues in a FTD model.

2 citationstop 2%

mouseexperimental assay

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NeurosciencebioRxivPreprintNov 1, 2024

Tcf4 Deficiency Causes Recurrent Seizures in Mice

Laura Craciun, Vivianna R. DeNittis, Matthew T. Davis…·Kaoru Saijo

This paper creates a PTHS mouse model with astrocyte-specific Tcf4 knockout, showing seizures, astrogliosis, increased neuronal activity, and gene expression changes.

DOI 10.1101/2024.11.01.621590

mousebulk RNA-seq

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