Sarah A. Naguib

This paper develops ROS-scavenging microparticles for sustained EPO release to treat glaucoma neurodegeneration, showing neuron preservation in animal models.

This study shows that transplanting wild-type human iPSC-derived microglia into progranulin-deficient mice reduces neuropathology, circuit dysfunction, and behavioral issues in a FTD model.

The paper identifies a role for prefrontal cortex astrocytes in stress resilience using mouse models and RNA-sequencing, showing distinct transcriptional responses between resilient and susceptible mice.

The R136S mutation on APOE3 enhances resistance to tau-related pathology and toxicity by downregulating the cGAS-STING-IFN signaling pathway.