lncRNA DIGIT and BRD3 protein form phase-separated condensates to regulate endoderm differentiation
Kaveh Daneshvar, M. Behfar Ardehali, Isaac A. Klein, Fu‐Kai Hsieh, Arcadia J. Kratkiewicz, Amin Mahpour, Sabrina Cancelliere, Chan Zhou, Brett M. Cook, Wenyang Li, Joshua V. Pondick, Sweta Gupta, Sean P. Moran, Richard A. Young, Robert E. Kingston, Alan C. Mullen
This study shows that lncRNA DIGIT and BRD3 form phase-separated condensates to regulate endoderm differentiation by interacting with H3K18ac regions.
Nature Cell Biology · Sep 7, 2020Peer-reviewedMolecular Biology