Role of Era in Assembly and Homeostasis of the Ribosomal Small Subunit
Aida Razi, Joseph H. Davis, Yumeng Hao, Dushyant Jahagirdar, Brett Thurlow, Kaustuv Basu, Nikhil Jain, Josué Gómez-Blanco, Robert A. Britton, Javier Vargas, Alba Guarné, Sarah A. Woodson, James R. Williamson, Joaquı́n Ortega
This study investigates Era's role in 30S ribosomal subunit assembly using mass spectrometry, cryo-EM, and in-cell footprinting, showing that most rRNA domains can fold without Era and that Era binding affects the decoding center.
Nucleic Acids Research · Jun 27, 2019Peer-reviewedMolecular Biology