Kaustuv Basu

This study uses cryo-ET and subtomogram averaging to determine the in situ architecture of the Tad pilus machine in Caulobacter crescentus, revealing its assembly intermediates and structural framework.

This study uses cryo-electron microscopy to determine the structure of the inactive conformation of the 30S ribosomal subunit and analyze its motions and structural changes under different conditions.

This study investigates Era's role in 30S ribosomal subunit assembly using mass spectrometry, cryo-EM, and in-cell footprinting, showing that most rRNA domains can fold without Era and that Era binding affects the decoding center.