Salmonella effector kinase SteC is activated by host-mediated phosphorylation
Timesh D Pillay, Briac Lemetais, Jessica Huber, Ines Diaz-del-Olmo, Yan Li, Laura Masino, Sarah Maslen, Mei Liu, Diego Esposito, Jay C. D. Hinton, Xiu‐Jun Yu, Teresa L. M. Thurston, Katrin Rittinger
This study identifies that Salmonella effector kinase SteC is activated by host-mediated phosphorylation at S379, which enhances its kinase activity and promotes actin polymerisation.
bioRxiv · Mar 1, 2025 · PreprintMicrobiology