EGFR confers exquisite specificity of Wnt9a-Fzd9b signaling in hematopoietic stem cell development
Stephanie J. Grainger, Nicole A Nguyen, Jenna Richter, Jordan Setayesh, Brianna Lonquich, Chet Huan Oon, Jacob M. Wozniak, Rocio A. Barahona, Caramai N. Kamei, Jack Houston, Marvic Carrillo-Terrazas, Iain A. S. Drummond, David J. Gonzalez, Karl Willert, David J. Traver
The paper shows EGFR is required for Wnt9a-Fzd9b signaling specificity in HSPC development, identifying key domains and phosphorylation events.
bioRxiv · Aug 7, 2018 · PreprintDevelopmental Biology