Author

Karl Willert

University of California San DiegoORCID 0000-0002-8020-6804Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Stephanie J. GraingeriD· 2 shared Anchel De Jaime-SogueroiD· 1 shared Anna Sophia JauchiD· 1 shared Brianna Lonquich· 1 shared Caramai N. Kamei· 1 shared Chet Huan OoniD· 1 shared Christina C. N. WuiD· 1 shared David J. GonzaleziD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersDevelopmental Biology

Stephanie J. GraingerORCID

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Author profile →

3 papers

Recent·Most cited

Long-term prevention of aneuploidy in human pluripotent stem cells by fine-tuning GSK3 activity

Anchel De Jaime-Soguero, Mírian Romitti, Sabine Costagliola, Anna Sophia Jauch, G. Vilangappurath, Karl Willert, F. Foijer, S.P. Acebrón

This study shows that low-dose GSK3 inhibitors prevent aneuploidy in hPSCs by reducing mitotic DNA synthesis and ultra-fine chromosome bridges during long-term culture.

bioRxiv · Oct 27, 2025 · PreprintCell Biology

Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells.

Diana Gumber, Myan Do, Neya Suresh Kumar, Pooja R. Sonavane, Christina C. N. Wu, Luisjesus S. Cruz, Stephanie J. Grainger, Dennis Anthony Carson, Terry Gaasterland, Karl Willert

eLife · Dec 17, 2020Peer-reviewedDevelopmental Biology

EGFR confers exquisite specificity of Wnt9a-Fzd9b signaling in hematopoietic stem cell development

Stephanie J. Grainger, Nicole A Nguyen, Jenna Richter, Jordan Setayesh, Brianna Lonquich, Chet Huan Oon, Jacob M. Wozniak, Rocio A. Barahona, Caramai N. Kamei, Jack Houston, Marvic Carrillo-Terrazas, Iain A. S. Drummond, David J. Gonzalez, Karl Willert, David J. Traver

The paper shows EGFR is required for Wnt9a-Fzd9b signaling specificity in HSPC development, identifying key domains and phosphorylation events.

bioRxiv · Aug 7, 2018 · PreprintDevelopmental Biology