In vivo measurements reveal a single 5’ intron is sufficient to increase protein expression level in C. elegans
Matthew M. Crane, Bryan Sands, Christian Battaglia, Brock Johnson, Soo R. Yun, Matt R. Kaeberlein, Roger Brent, Alexander Mendenhall
The paper quantifies Intron Mediated Enhancement (IME) in C. elegans by measuring protein expression levels using fluorescent reporters and finds a single intron can increase expression by about 50%.
Scientific Reports · Jun 24, 2019Peer-reviewedGenetics