Author

Byron Butaney

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

Brian D. CromptoniD· 2 shared Natalie Bucheimer CollinsiD· 2 shared Riaz GillaniiD· 2 shared Shreya Raman· 2 shared Yutaro TanakaiD· 2 shared Aaron R. ThorneriD· 1 shared Amanda GarzaiD· 1 shared Amr Salem· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Brian D. CromptonORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Clustered structural variant hotspots enable oncogenic addiction and plasticity in osteosarcoma

Shreya Raman, Thorsten Kaltenbacher, David Merrell, Kavya Prasad, Yutaro Tanaka, Jakob Weiss, Emily Iannetta, Byron Butaney, Emily Jorswieck, Amr Salem, Lorena Lazo de la Vega, Evelina Ceca, Julia MW Wong, Suzanne J. Forrest, Kelly S. Klega, , Riaz Gillani

The paper identifies clustered structural variant hotspots in osteosarcoma, linking them to oncogenic addiction and plasticity through transcriptional changes and clinical detectability.

bioRxiv · Sep 18, 2026 · PreprintCancer Biology

Metastatic Osteosarcoma is Characterized by Loss of Osteoblastic Lineage Fidelity

Yutaro Tanaka, James J. Morrow, Salvador Casaní-Galdón, Erica Maria Pimenta, Jiayi Li, Byron Butaney, Chadi A. El Farran, Julie Karam, Joshua P. D’Antonio, Kevin Bi, Laura Valderrábano, Sabrina Yvonne Camp, Yun Jee Kang, Shreya Johri, Lester Heredia Gopar, , Riaz Gillani

This study identifies a loss of osteoblastic lineage fidelity in metastatic osteosarcoma through single-nucleus RNA sequencing, linking it to disease progression and potential therapeutic targets.

bioRxiv · Jun 12, 2026 · PreprintCancer Biology

scGrapHiC: Deep learning-based graph deconvolution for Hi-C using single cell gene expression

Ghulam Murtaza, Byron Butaney, Justin Wagner, Ritambhara Singh

scGrapHiC uses deep learning to predict cell-type-specific scHi-C contact maps from scRNA-seq data, improving recovery of Topologically Associating Domains by 23.2% over baselines.

Bioinformatics · Jun 28, 2024Peer-reviewedGenomics