Author

Yun Jee Kang

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:statistical model· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Aaron R. ThorneriD· 3 shared Amanda GarzaiD· 3 shared Breanna M. TitcheniD· 3 shared Eliezer M. Van AlleniD· 3 shared Erica Maria PimentaiD· 3 shared Kevin BiiD· 3 shared Sabrina Yvonne CampiD· 3 shared Anwesha NagiD· 2 shared

Activity by Year

2025-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Aaron R. ThornerORCID

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Author profile →

5 papers

Recent·Most cited

Metastatic Osteosarcoma is Characterized by Loss of Osteoblastic Lineage Fidelity

Yutaro Tanaka, James J. Morrow, Salvador Casaní-Galdón, Erica Maria Pimenta, Jiayi Li, Byron Butaney, Chadi A. El Farran, Julie Karam, Joshua P. D’Antonio, Kevin Bi, Laura Valderrábano, Sabrina Yvonne Camp, Yun Jee Kang, Shreya Johri, Lester Heredia Gopar, , Riaz Gillani

This study identifies a loss of osteoblastic lineage fidelity in metastatic osteosarcoma through single-nucleus RNA sequencing, linking it to disease progression and potential therapeutic targets.

bioRxiv · Jun 12, 2026 · PreprintCancer Biology

Epigenetic Gatekeeping of Wnt-Responsive Enhancers Restricts Intestinal Stem Cell Transformation

Alireza Lorzadeh, Sweta Sharma, George Ye, Sabrina Rabaya, Yun Jee Kang, Ramesh A. Shivdasani, Unmesh Jadhav

This study identifies H3K27me3 as an epigenetic barrier that restricts intestinal stem cell transformation by maintaining enhancer repression and preventing fetal gene reactivation in colorectal cancer.

bioRxiv · Jun 8, 2026 · PreprintCancer Biology

Single-cell epigenetic profiling reveals an interferon response-high program associated with BAP1 deficiency in kidney cancer

Sabrina Yvonne Camp, Meng Xiao He, Michael S. Cuoco, Amanda Garza, Simayijiang Xirenayi, Ziad Bakouny, Eddy Saad, Jad El Masri, Erica Maria Pimenta, Kevin Meli, Chris Labaki, Breanna M. Titchen, Yun Jee Kang, Jack T. Horst, Rachel Trowbridge, , Eliezer M. Van Allen

The paper identifies an IFN response-high epigenetic program linked to BAP1 deficiency in kidney cancer using single nucleus ATAC sequencing across multiple cohorts.

Science Advances · Feb 20, 2026Peer-reviewedCancer Biology

Epigenetic dysregulation of metabolic programs mediates liposarcoma cell plasticity

Erica Maria Pimenta, Amanda Garza, Sabrina Yvonne Camp, Jihye Park, Samantha E. Hoffman, Laura Valderrábano, Jingxin Fu, Kevin Bi, Maximilian Carson, Julie Karam, Breanna M. Titchen, Sofia Medjahed, Melin Janardan Khandekar, Erin E. Shannon, Yun Jee Kang, , Eliezer M. Van Allen

This study identifies epigenetic dysregulation of metabolic programs in liposarcoma, linking IGF1 loss and PPARG2 deficiency to dedifferentiation and proposing IGF1R-targeted therapy.

Science Translational Medicine · Jan 21, 2026Peer-reviewedCancer Biology

LISA: A Comprehensive R Package for Lentiviral Integration Site Analysis in Gene Therapy Safety Assessment

Shuai Ni, Ning Wu, Yun Jee Kang, Fengjiao Zhu, Jueyu Wang, Lina Wang, Wei Wang, Heng Mei, Kejia Kan

LISA is an R package for analyzing lentiviral integration sites in gene therapy to assess safety by identifying risk-associated genomic regions and tracking clonal dynamics.

bioRxiv · Dec 23, 2025 · PreprintBioinformatics