Author
Inserm
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Eugénie Schaeffer, Elsa Barré, Desline Hennequin…·Alexandra Mazharian
This study uses CRISPR/Cas9 to delete Shp1 and Shp2 in human CD34+ cells, showing Shp2 is critical for megakaryopoiesis and thrombopoiesis while Shp1 is not.
Elsa Barré, Marc‐Damien Lourenco‐Rodrigues, Lucie Zimmermann…·Alexandra Mazharian
This study shows that deleting Shp1 and Shp2 in mice impairs megakaryopoiesis and thrombopoiesis, leading to macrothrombocytopenia and reduced platelet function.
Alexandra Mazharian, Ophélie Bertin, Amrita Sarkar…·Yotis A. Senis
This study introduces CAPRIs, bispecific antibodies that inhibit platelet activation by clustering G6B with ITAM receptors, showing effectiveness in preventing thrombus formation without causing bleeding.