Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters
Neil C. Dalvie, Sergio A. Rodriguez‐Aponte, Brittany L. Hartwell, Lisa H. Tostanoski, Andrew M. Biedermann, Laura E. Crowell, Kawaljit Kaur, Ozan S. Kumru, Lauren P. Carter, Jingyou Yu, Aiquan Chang, Katherine McMahan, Thomas Courant, Célia Lebas, Ashley A. Lemnios, , John Christopher Love
This paper describes an engineered SARS-CoV-2 RBD variant that shows improved immunogenicity in mice and protective immunity in hamsters.
bioRxiv · Mar 3, 2021 · PreprintMolecular Biology