An intravenous DNA-binding priming agent protects cell-free DNA and improves the sensitivity of liquid biopsies
Shervin Tabrizi, Carmen Martin-Alonso, Kan Xiong, Timothy Blewett, Sainetra Sridhar, Zhenyi An, Sahil Patel, Sergio A. Rodriguez‐Aponte, Christopher A. Naranjo, Shih‐Ting Wang, Douglas Shea, Todd R. Golub, Sangeeta N. Bhatia, Viktor A. Adalsteinsson, John Christopher Love
A DNA-binding agent increases cfDNA levels in blood, improving ctDNA detection and cancer sensitivity in mice.
bioRxiv · Jan 13, 2023 · PreprintGenomics