Characterizing Adeno-Associated Virus Capsids with both Denaturing and Intact Analysis Methods
J. P. Ryan, M. M. Kostelic, C.-C. Hsieh, J. B. Powers, C. A. Aspinwall, J. N. Dodds, J. E. Schiel, M. T. Marty, E. S. Baker
The paper combines two analytical methods to characterize AAV capsids and their subunits, evaluating capsid integrity and VP sequence variations across three serotypes.
Journal of the American Society for Mass Spectrometry · Nov 27, 2023Peer-reviewedBiochemistry