Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
34 papers
Recent·Most cited
B. S. Nelson, L. Lin, D. M. Kremer…·C. A. Lyssiotis
The paper shows that pancreatic ductal adenocarcinoma (PDA) is more dependent on GOT1 than colorectal cancer (CRC) and that GOT1 inhibition synergizes with radiotherapy to inhibit PDA growth.
M. A. Badgley, D. Kremer, H. C. Maurer…·K. P. Olive
The paper shows that targeting cystine import induces ferroptosis in pancreatic tumors, leading to tumor regression and improved survival in a mouse model.
R. Singhal, K. P. Olive, C. A. Lyssiotis, Y. M. Shah
This study shows that HIF-2α overexpression makes colon cancer cells more sensitive to oxidative cell death, suggesting a potential therapeutic strategy.
C. J. Halbrook, C. Pontious, H.-J. Lee…·C. A. Lyssiotis
This study shows macrophages in pancreatic cancer release pyrimidines that inhibit gemcitabine therapy by competing with the drug for uptake and metabolism, and reducing macrophage burden improves treatment response.