PDX models reflect the proteome landscape of pediatric acute lymphoblastic leukemia but divert in select pathways
A. C. Uzozie, E. K. Ergin, N. Rolf, A. Lorentzian, S. S. Weng, L. Nierves, T. G. Smith, C. J. Lim, C. A. Maxwell, G. S. Reid, P. F. Lange
This study compares proteome and post-translational modification landscapes between pediatric leukemia patients and their xenograft models, finding both similarities and key divergences.
bioRxiv · Dec 18, 2019Cancer Biology