Mapping the substrate landscape of protein phosphatase 2A catalytic subunit PPP2CA
A. Brewer, G. Sathe, B. E. Pflug…·G. P. Sapkota
The paper identifies 2,204 potential PPP2CA substrates using proteolysis-targeting chimeras and phospho-proteomic analysis, revealing novel substrates and a pSP/pTP motif preference.