Quantification of within patient Staphylococcus aureus phenotypic heterogeneity as a proxy for presence of persisters across clinical presentations
J. Baer, M. Boumasmoud, S. Mairpady Shambat, C. Vulin, M. Huemer, T. A. Schweizer, A. Gómez Mejia, N. Eberhard, Y. Achermann, P. O. Zingg, C. A. Mestres, S. D. Brugger, R. A. Schüpbach, R. D. Kouyos, B. Hasse, A. S. Zinkernagel
This study quantifies phenotypic heterogeneity in Staphylococcus aureus from patient samples to assess persisters, finding that rifampicin treatment correlates with increased growth delays.
bioRxiv · Jul 27, 2021Microbiology