Author

C. Buyck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

D. Bojkova· 2 shared D. Jochmans· 2 shared E. Van Damme· 2 shared J. Cinatl· 2 shared J. Neyts· 2 shared M. Van Loock· 2 shared P. Leyssen· 2 shared S. Ciesek· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

D. Bojkova

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2 papers

Recent·Most cited

Development and optimisation of a high-throughput screening assay for in vitro anti-SARS-CoV-2 activity: evaluation of 5676 phase 1 passed structures

W. Chiu, L. Verschueren, C. Van den Eynde, C. Buyck, S. De Meyer, D. Jochmans, D. Bojkova, S. Ciesek, J. Cinatl, S. De Jonghe, P. Leyssen, J. Neyts, M. Van Loock, E. Van Damme

The paper develops a high-throughput screening assay to evaluate 5676 phase 1 compounds for in vitro anti-SARS-CoV-2 activity, identifying eight candidates but finding only remdesivir suitable for further clinical development.

bioRxiv · Feb 2, 2022Immunology

In Vitro Activity of Itraconazole Against SARS-CoV-2

E. Van Damme, S. De Meyer, D. Bojkova, S. Ciesek, J. Cinatl, S. De Jonghe, D. Jochmans, P. Leyssen, C. Buyck, J. Neyts, M. Van Loock

This paper assesses the in vitro antiviral activity of itraconazole and its metabolite against SARS-CoV-2, finding EC50 values of 2.3 μM and 3.6 μM, respectively, and reports no clinical efficacy in hospitalized patients.

bioRxiv · Nov 13, 2020Pharmacology & Toxicology