Author

C. C. H. Langer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Organism:human· 1

Frequent Co-Authors

C. Blaukopf· 2 shared D. W. Gerlich· 2 shared B. A. Gibson· 1 shared J.-M. Peters· 1 shared L. K. Doolittle· 1 shared M. F. D. Spicer· 1 shared M. K. Rosen· 1 shared M. Petrovic· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

C. Blaukopf

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2 papers

Recent·Most cited

Cohesin-mediated DNA loop extrusion resolves sister chromatids in G2 phase

P. Batty, C. C. H. Langer, Z. Takacs, W. Tang, C. Blaukopf, J.-M. Peters, D. W. Gerlich

This study shows cohesin-mediated DNA loop extrusion resolves sister chromatids in G2 phase, independent of condensins, suggesting loop extrusion is a general mechanism for genome segregation.

bioRxiv · Jan 12, 2023Cell Biology

A chromatin phase transition protects mitotic chromosomes against microtubule perforation

M. W. G. Schneider, B. A. Gibson, S. Otsuka, M. F. D. Spicer, M. Petrovic, C. Blaukopf, C. C. H. Langer, L. K. Doolittle, M. K. Rosen, D. W. Gerlich

This study shows that global histone deacetylation during mitosis induces a chromatin phase transition that protects chromosomes from microtubule perforation and ensures proper segregation.

bioRxiv · Jul 5, 2021 · PreprintCell Biology