Author

C. C. Hayden

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 3 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

J. C. Stachowiak· 3 shared E. M. Lafer· 2 shared G. Ashby· 2 shared J. R. Houser· 2 shared J. Stachowiak· 2 shared K. E. Keng· 2 shared L. Wang· 2 shared D. Thirumalai· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersBiophysics

J. C. Stachowiak

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5 papers

Recent·Most cited

A live cell imaging-based assay for tracking particle uptake by clathrin-mediated endocytosis

G. Ashby, K. E. Keng, C. C. Hayden, J. Stachowiak

This paper introduces a live-cell imaging assay using TIRF microscopy to track particle uptake by clathrin-mediated endocytosis and analyzes how particle properties affect uptake efficiency.

bioRxiv · Feb 8, 2024 · PreprintBiophysics

Selective endocytic uptake of targeted liposomes occurs within a narrow range of liposome diameter

G. Ashby, K. E. Keng, C. C. Hayden, S. Gollapudi, J. R. Houser, S. Jamal, J. Stachowiak

The paper uses live-cell imaging to show that liposome diameter, not ligand density, primarily determines their endocytic uptake, with targeting most effective for intermediate-sized liposomes.

bioRxiv · Jul 6, 2023Bioengineering

Lateral compression of lipids drives transbilayer coupling of liquid-like protein condensates

Y. Lee, S. Park, F. Yuan, C. C. Hayden, S. Q. Choi, J. C. Stachowiak

This study shows that protein phase separation on both sides of a lipid bilayer is coupled through an entropic mechanism driven by lipid compression.

bioRxiv · Dec 21, 2022Biophysics

Molecular Mechanisms of Steric Pressure Generation and Membrane Remodeling by Intrinsically Disordered Proteins

J. R. Houser, H. W. Cho, C. C. Hayden, N. Yang, L. Wang, E. M. Lafer, D. Thirumalai, J. C. Stachowiak

This study measures steric pressure generated by intrinsically disordered domains of AP180 at membrane surfaces, finding that they produce significant pressure through entropic and electrostatic mechanisms, independent of molecular weight.

Biophysical Journal · Sep 1, 2022Peer-reviewedBiophysics

Liquid-like protein interactions catalyze assembly of endocytic vesicles

K. J. Day, G. Kago, L. Wang, J. B. Richter, C. C. Hayden, E. M. Lafer, J. C. Stachowiak

The paper shows that weak, liquid-like interactions between Eps15 and Fcho1 enable efficient endocytosis by promoting dynamic protein assembly and preventing stalling of vesicle budding.

bioRxiv · Dec 2, 2019Cell Biology