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Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
K. Graham, A. Chandrasekaran, L. Wang, N. Yang, E. M. Lafer, P. Rangamani, J. C. Stachowiak
This study shows that liquid-like condensates containing both actin branching and bundling proteins can modulate the competition between these processes, leading to organized actin structures similar to those in migrating cells.
Proceedings of the National Academy of Sciences · Jan 11, 2024Peer-reviewedBiophysics
M. L. Mugnai, D. Chakraborty, A. Kumar, H. T. Nguyen, W. Zeno, J. C. Stachowiak, J. E. Straub, D. Thirumalai
This paper develops a transferable model to predict biophysical properties of IDPs, showing agreement with experimental data on size, conformation, and SAXS profiles.
bioRxiv · Apr 24, 2023Biophysics
Y. Lee, S. Park, F. Yuan, C. C. Hayden, S. Q. Choi, J. C. Stachowiak
This study shows that protein phase separation on both sides of a lipid bilayer is coupled through an entropic mechanism driven by lipid compression.
bioRxiv · Dec 21, 2022Biophysics
J. R. Houser, H. W. Cho, C. C. Hayden, N. Yang, L. Wang, E. M. Lafer, D. Thirumalai, J. C. Stachowiak
This study measures steric pressure generated by intrinsically disordered domains of AP180 at membrane surfaces, finding that they produce significant pressure through entropic and electrostatic mechanisms, independent of molecular weight.
Biophysical Journal · Sep 1, 2022Peer-reviewedBiophysics
K. D. Graham, A. Chandrasekaran, L. Wang, A. Ladak, E. M. Lafer, P. Rangamani, J. C. Stachowiak
This study shows VASP forms liquid-like droplets that drive actin polymerization and bundling by creating actin-rich rings that transition into linear bundles.
bioRxiv · May 9, 2022Biophysics
F. Yuan, H. Alimohamadi, B. Bakka, A. N. Trementozzi, N. L. Fawzi, P. Rangamani, J. C. Stachowiak
This paper investigates how liquid-like protein assemblies on membranes drive membrane bending by creating compressive stress, leading to the formation of membrane tubules.
bioRxiv · May 21, 2020Biophysics
V. Le, L. Mei, P. L. Voyvodic, C. Zhao, D. J. Busch, J. C. Stachowiak, A. B. Baker
This study investigates how syndecan-1 mechanical tension responds to substrate stiffness and fluidic shear stress in endothelial cells.
bioRxiv · May 9, 2020Bioengineering
K. J. Day, G. Kago, L. Wang, J. B. Richter, C. C. Hayden, E. M. Lafer, J. C. Stachowiak
The paper shows that weak, liquid-like interactions between Eps15 and Fcho1 enable efficient endocytosis by promoting dynamic protein assembly and preventing stalling of vesicle budding.
bioRxiv · Dec 2, 2019Cell Biology
W. T. Snead, W. F. Zeno, G. Kago, R. W. Perkins, J. B. Richter, C. Zhao, E. M. Lafer, J. C. Stachowiak
The paper shows that BAR domain-containing proteins drive membrane fission by crowding disordered domains, challenging the idea that BAR scaffolds stabilize membranes.
bioRxiv · Jul 16, 2018Biophysics