C. C. Mendes

APP and β-amyloid modulate protein aggregation and dissociation from recycling endosomal and exosomal membranes

The paper shows APP and Aβ-peptides modulate protein aggregation and DCG biogenesis in Drosophila cells, with mutant Aβ-peptides disrupting these processes and causing AD-like pathologies.

A Rab6 to Rab11 transition is required for dense-core granule and exosome biogenesis in Drosophila secondary cells

The paper studies DCG biogenesis in Drosophila secondary cells, identifying a Rab6 to Rab11 transition essential for DCG and exosome formation.

Rbf/E2F1 control growth and endoreplication via steroid-independent Ecdysone Receptor signalling in Drosophila prostate-like secondary cells

This study shows that Rbf/E2F1 and cell cycle regulators control growth and endoreplication in Drosophila secondary cells via steroid-independent EcR signalling, mirroring mechanisms in castration-resistant prostate cancer.

Unravelling the genetic basis for the rapid diversification of male genital structures between Drosophila species

The paper identifies genes involved in the development and evolution of male genital structures in Drosophila species using introgression lines and RNA-seq.

Accessory ESCRT-III proteins selectively regulate Rab11-exosome biogenesis in Drosophila secondary cells

This study identifies accessory ESCRT-III proteins as essential for Rab11-exosome biogenesis in Drosophila secondary cells, distinct from core ESCRT functions.

Drosophila Sex Peptide Controls the Assembly of Lipid Microcarriers in Seminal Fluid

This paper shows that Sex Peptide in Drosophila is essential for assembling lipid microcarriers in seminal fluid, which are transferred to females and disassembled, with SP also required for normal female disassembly.

tartan underlies the evolution of male Drosophila genital morphology

This paper identifies the gene tartan as responsible for evolutionary differences in male Drosophila genital morphology between D. mauritiana and D. simulans.