Author

C. Cassioli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Cancer Biology· 1

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Research Focus:cell type annotation· 5 Organism:human· 5 Assay:proteomics· 4 Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. T. Baldari· 5 shared A. Onnis· 4 shared G. Marotta· 3 shared E. B. Compeer· 2 shared F. Finetti· 2 shared M. L. Dustin· 2 shared N. Capitani· 2 shared A. Amedei· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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5 shared papersImmunology

C. T. Baldari

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Author profile →

5 papers

Recent·Most cited

Thrombospondins 1 and 4 undergo coordinated transport to multicore cytotoxic granules to regulate SMAP biogenesis and function in CTL-mediatedcytotoxicity

C. Cassioli, N. Capitani, C. C. Staton, C. Schirra, F. Finetti, A. Onnis, N. Alawar, S.-M. Tu, L. Lopresti, V. Tatangelo, C. Tangredi, S. Valvo, H.-F. Chang, A. Miccoli, E. B. Compeer, , C. T. Baldari

This study shows TSP-4 is required for TSP-1 association with lytic granules and SMAP-mediated cytotoxicity in CTLs, and its expression is suppressed in CLL cell supernatants.

bioRxiv · Apr 25, 2024 · PreprintImmunology

Human colorectal cancer: upregulation of the adaptor protein Rai in TILs leads to cell dysfunction by sustaining GSK-3 activation and PD-1 expression

T. Montecchi, G. Nannini, D. De Tommaso, C. Cassioli, F. Coppola, M. N. Rigressi, F. Carraro, A. Naldini, A. Taddei, G. Marotta, A. Amedei, C. T. Baldari, C. Ulivieri

This study identifies Rai as a novel HIF-1-responsive gene upregulated in CRC TILs, which promotes T cell exhaustion by sustaining GSK-3 activation and PD-1 expression.

bioRxiv · Jun 23, 2023Cancer Biology

SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly

A. Onnis, E. Andreano, C. Cassioli, E. Pantano, V. Abbiento, G. Marotta, R. Rappuoli, C. T. Baldari

This study shows SARS-CoV-2 Spike protein inhibits CTL immune synapse formation by binding ACE2, reducing target cell killing.

bioRxiv · May 20, 2022Immunology

The Bardet-Biedl Syndrome complex component BBS1 regulates proteasome-dependent F-actin clearance from the centrosome to enable its translocation to the T cell immune synapse

C. Cassioli, A. Onnis, F. Francesca, N. Capitani, E. B. Compeer, M. L. Dustin, C. T. Baldari

bioRxiv · Nov 30, 2020 · PreprintImmunology

The intraflagellar transport protein IFT20 recruits ATG16L1 to early endosomes to promote autophagosome formation in T cells

F. Finetti, C. Cassioli, V. Cianfanelli, F. Zevolini, A. Onnis, M. Gesualdo, J. Brunetti, F. Cecconi, C. T. Baldari

bioRxiv · Nov 26, 2020Immunology