Author

A. Onnis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Organism:human· 5 Assay:proteomics· 5 Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. Cassioli· 4 shared C. T. Baldari· 4 shared F. Finetti· 3 shared G. Marotta· 3 shared E. B. Compeer· 2 shared F. Zevolini· 2 shared M. L. Dustin· 2 shared N. Capitani· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersImmunology

C. Cassioli

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Thrombospondins 1 and 4 undergo coordinated transport to multicore cytotoxic granules to regulate SMAP biogenesis and function in CTL-mediatedcytotoxicity

C. Cassioli, N. Capitani, C. C. Staton, C. Schirra, F. Finetti, A. Onnis, N. Alawar, S.-M. Tu, L. Lopresti, V. Tatangelo, C. Tangredi, S. Valvo, H.-F. Chang, A. Miccoli, E. B. Compeer, , C. T. Baldari

This study shows TSP-4 is required for TSP-1 association with lytic granules and SMAP-mediated cytotoxicity in CTLs, and its expression is suppressed in CLL cell supernatants.

bioRxiv · Apr 25, 2024 · PreprintImmunology

Polo-like kinase 1 regulates immune synapse assembly and cytotoxic T cell function by driving microtubule dynamics

F. Zevolini, A. Onnis, R. Khazen, S. Mueller, G. Marotta, S. Valiltutti, F. Finetti, C. Baldari

This study shows that Polo-like kinase 1 (PLK1) is essential for immune synapse (IS) assembly and cytotoxic T cell function by regulating microtubule dynamics during IS formation.

bioRxiv · Jul 12, 2023Immunology

SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly

A. Onnis, E. Andreano, C. Cassioli, E. Pantano, V. Abbiento, G. Marotta, R. Rappuoli, C. T. Baldari

This study shows SARS-CoV-2 Spike protein inhibits CTL immune synapse formation by binding ACE2, reducing target cell killing.

bioRxiv · May 20, 2022Immunology

The Bardet-Biedl Syndrome complex component BBS1 regulates proteasome-dependent F-actin clearance from the centrosome to enable its translocation to the T cell immune synapse

C. Cassioli, A. Onnis, F. Francesca, N. Capitani, E. B. Compeer, M. L. Dustin, C. T. Baldari

bioRxiv · Nov 30, 2020 · PreprintImmunology

The intraflagellar transport protein IFT20 recruits ATG16L1 to early endosomes to promote autophagosome formation in T cells

F. Finetti, C. Cassioli, V. Cianfanelli, F. Zevolini, A. Onnis, M. Gesualdo, J. Brunetti, F. Cecconi, C. T. Baldari

bioRxiv · Nov 26, 2020Immunology