Author

C. T. Baldari

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 7 Approach:experimental assay· 6 Assay:proteomics· 6 Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. Cassioli· 4 shared A. Onnis· 3 shared F. Finetti· 3 shared G. Marotta· 3 shared C. Ulivieri· 2 shared G. Boncompagni· 2 shared N. Capitani· 2 shared T. Montecchi· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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4 shared papersImmunology

C. Cassioli

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Human monoclonal antibodies reveal subdominant gonococcal and meningococcal cross-protective antigens

M. Troisi, M. Fabbrini, S. Stazzoni, V. Viviani, F. Carboni, V. Abbiento, L. E. Fontana, S. Tomei, M. Audagnotto, L. Santini, A. Spagnuolo, G. Antonelli, I. Paciello, F. Vacca, D. Cardamone, , An

The paper identifies human monoclonal antibodies that recognize key antigens, PorB and LOS, providing cross-protection against gonococcal and meningococcal infections.

bioRxiv · Dec 7, 2023 · PreprintImmunology

Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia

G. Boncompagni, V. Tatangelo, L. Lopresti, C. Ulivieri, N. Capitani, C. Tangredi, F. Finetti, G. Marotta, F. Frezzato, A. Visentin, S. Ciofini, A. Gozzetti, M. Bocchia, D. Calzada-Fraile, N. B. Martin Cofreces, , C. T. Baldari

This study shows that IL-9 secreted by leukemic cells suppresses CTL-mediated killing in CLL by increasing PD-1 expression and impairing immune synapse formation.

bioRxiv · Oct 23, 2023 · PreprintCancer Biology

Human colorectal cancer: upregulation of the adaptor protein Rai in TILs leads to cell dysfunction by sustaining GSK-3 activation and PD-1 expression

T. Montecchi, G. Nannini, D. De Tommaso, C. Cassioli, F. Coppola, M. N. Rigressi, F. Carraro, A. Naldini, A. Taddei, G. Marotta, A. Amedei, C. T. Baldari, C. Ulivieri

This study identifies Rai as a novel HIF-1-responsive gene upregulated in CRC TILs, which promotes T cell exhaustion by sustaining GSK-3 activation and PD-1 expression.

bioRxiv · Jun 23, 2023Cancer Biology

SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly

A. Onnis, E. Andreano, C. Cassioli, E. Pantano, V. Abbiento, G. Marotta, R. Rappuoli, C. T. Baldari

This study shows SARS-CoV-2 Spike protein inhibits CTL immune synapse formation by binding ACE2, reducing target cell killing.

bioRxiv · May 20, 2022Immunology

The Bardet-Biedl Syndrome complex component BBS1 regulates proteasome-dependent F-actin clearance from the centrosome to enable its translocation to the T cell immune synapse

C. Cassioli, A. Onnis, F. Francesca, N. Capitani, E. B. Compeer, M. L. Dustin, C. T. Baldari

bioRxiv · Nov 30, 2020 · PreprintImmunology

The intraflagellar transport protein IFT20 recruits ATG16L1 to early endosomes to promote autophagosome formation in T cells

F. Finetti, C. Cassioli, V. Cianfanelli, F. Zevolini, A. Onnis, M. Gesualdo, J. Brunetti, F. Cecconi, C. T. Baldari

bioRxiv · Nov 26, 2020Immunology

Phosphoproteomics of CD2 signaling reveals an AMPK-dependent regulation of lytic granule polarization in cytotoxic T cells

V. Zurli, T. Montecchi, R. Heilig, I. Poschke, M. Volkmar, G. Wimmer, G. Boncompagni, G. Turacchio, M. M. D'Elios, G. Campoccia, N. Resta, R. Offringa, R. Fischer, O. Acuto, C. T. Baldari, A. Kabanova

bioRxiv · Oct 8, 2019Immunology