Author

C. Chinopoulos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1

Frequent Co-Authors

D. Bui· 3 shared N. Karnok· 3 shared T. N. Seyfried· 3 shared B. Czumbel· 2 shared B. Greenwood· 2 shared G. Pallag· 2 shared N. R. Narain· 2 shared S. Nazarian· 2 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

D. Bui

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Amino Acid and Glucose Fermentation Maintain ATP Content in Mouse and Human Malignant Glioma Cells

D. C. Lee, L. Ta, P. Mukherjee, T. Duraj, M. Domin, B. Greenwood, S. Karmacharya, N. R. Narain, M. Kiebish, C. Chinopoulos, T. N. Seyfried

This study shows that malignant glioma cells rely on amino acid and glucose fermentation for ATP production, not oxidative phosphorylation, and that glutamine is essential for maintaining ATP content and viability.

bioRxiv · Apr 18, 2024Cancer Biology

RPPA survey of cancer hotspot panel proteins and cell markers in matched tumor-normal human breast and kidney samples reveals a weak correlation between proteins expression and public transcriptome repositories

K. Paal, C. Konrad, N. Karnok, D. Bui, C. Chinopoulos

The paper correlates protein expression from RPPA with transcriptome data from public repositories in breast and kidney cancer samples, finding weak correlations between protein and gene expression.

bioRxiv · Nov 9, 2023 · PreprintCancer Biology

Viability of HepG2 and MCF-7 Cells is not Correlated with Mitochondrial Bioenergetics

J. Doczi, N. Karnok, D. Bui, V. Azarov, G. Pallag, S. Nazarian, B. Czumbel, T. N. Seyfried, C. Chinopoulos

This study shows that mitochondrial bioenergetics and cell viability are uncorrelated in HepG2 and MCF-7 cancer cells under various metabolic stress conditions.

Scientific Reports · Jul 4, 2023Peer-reviewedCancer Biology

Residual Complex I activity supports glutamate catabolism and mtSLP via canonical Krebs cycle activity during acute anoxia without OXPHOS

D. Ravasz, D. Bui, S. Nazarian, G. Pallag, N. Karnok, J. Roberts, D. A. Tennant, B. Greenwood, A. Kitayev, C. Hill, T. Komlodi, C. Doerrier, E. Gnaiger, M. A. Kiebish, A. Raska, , C. Chinopoulos

The paper shows that residual Complex I activity sustains glutamate catabolism and mtSLP during acute anoxia by oxidizing NADH with endogenous quinones, bypassing OXPHOS.

bioRxiv · Sep 26, 2022 · PreprintBiochemistry