Author

B. Greenwood

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:metabolomics· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:metabolism & bioenergetics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

M. A. Kiebish· 3 shared J.-T. A. Chi· 2 shared N. R. Narain· 2 shared P.-H. Lin· 2 shared S. Freedland· 2 shared T. N. Seyfried· 2 shared V. Bussberg· 2 shared V. Tolstikov· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersCancer Biology

M. A. Kiebish

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Author profile →

5 papers

Recent·Most cited

Ketogenic diet as a metabolic vehicle for enhancing the therapeutic efficacy of mebendazole and devimistat in preclinical high-grade gliomas grown in juvenile mice

P. Mukherjee, J. Maurer, S. A. Stopka, B. Greenwood, J. J. A. Henao, S. Karmacharya, A. Chimento, N. Ta, D. C. Lee, T. Duraj, R. T. Bronson, M. A. Kiebish, T. N. Seyfried

This study shows that combining a ketogenic diet with mebendazole or devimistat improves therapeutic outcomes in preclinical high-grade glioma models in juvenile mice.

bioRxiv · Jun 9, 2023 · PreprintCancer Biology

Residual Complex I activity supports glutamate catabolism and mtSLP via canonical Krebs cycle activity during acute anoxia without OXPHOS

D. Ravasz, D. Bui, S. Nazarian, G. Pallag, N. Karnok, J. Roberts, D. A. Tennant, B. Greenwood, A. Kitayev, C. Hill, T. Komlodi, C. Doerrier, E. Gnaiger, M. A. Kiebish, A. Raska, , C. Chinopoulos

The paper shows that residual Complex I activity sustains glutamate catabolism and mtSLP during acute anoxia by oxidizing NADH with endogenous quinones, bypassing OXPHOS.

bioRxiv · Sep 26, 2022 · PreprintBiochemistry

Serum metabolomic analysis of men on a low-carbohydrate diet for biochemically recurrent prostate cancer reveal the potential role of ketogenesis to slow tumor growth: A secondary analysis of the CAPS2 diet trial

J.-T. A. Chi, P.-H. Lin, V. Tolstikov, L. Howard, E. Y. Chen, V. Bussberg, B. Greenwood, N. R. Narain, M. A. Kiebish, S. Freedland

This paper analyzes serum metabolomics from a low-carbohydrate diet trial in prostate cancer patients to identify metabolic changes associated with slower tumor growth.

bioRxiv · Dec 29, 2021Cancer Biology

The effects of low-carbohydrate diets on the metabolic response to androgen-deprivation therapy in prostate cancer

J.-T. A. Chi, P.-H. Lin, V. Tolstikov, T. Oyekunle, G. Galvan, A. Ramirez-Torres, E. Chen, V. Bussberg, B. Chi, B. Greenwood, R. Sarangarajan, N. Narain, M. Kiebish, S. Freedland

This study investigates how low-carbohydrate diets affect metabolic changes in prostate cancer patients undergoing androgen deprivation therapy, finding that the diet reverses some adverse metabolic effects while slightly lowering androgen levels.

bioRxiv · Sep 23, 2020 · PreprintCancer Biology

THE ROLE OF POTASSIUM CHANNELS IN THE PATHOGENESIS OF GASTROINTESTINAL CANCERS AND THERAPEUTIC POTENTIAL

D. Shorthouse, J. L. Zhuang, E. Rahrmann, C. Kosmidou, K. W. Rahrmann, M. W. J. Hall, B. Greenwood, G. Devonshire, R. Gilbertson, R. Fitzgerald, B. A. Hall

The paper identifies KCNQ channel mutations in 30% of gastrointestinal cancers and shows their therapeutic targetability through drug sensitivity and proliferation inhibition.

bioRxiv · Mar 10, 2020 · PreprintCancer Biology