Author

T. Duraj

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

B. Greenwood· 2 shared D. C. Lee· 2 shared P. Mukherjee· 2 shared S. Karmacharya· 2 shared T. N. Seyfried· 2 shared A. Chimento· 1 shared C. Chinopoulos· 1 shared J. J. A. Henao· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

B. Greenwood

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2 papers

Recent·Most cited

Amino Acid and Glucose Fermentation Maintain ATP Content in Mouse and Human Malignant Glioma Cells

D. C. Lee, L. Ta, P. Mukherjee, T. Duraj, M. Domin, B. Greenwood, S. Karmacharya, N. R. Narain, M. Kiebish, C. Chinopoulos, T. N. Seyfried

This study shows that malignant glioma cells rely on amino acid and glucose fermentation for ATP production, not oxidative phosphorylation, and that glutamine is essential for maintaining ATP content and viability.

bioRxiv · Apr 18, 2024Cancer Biology

Ketogenic diet as a metabolic vehicle for enhancing the therapeutic efficacy of mebendazole and devimistat in preclinical high-grade gliomas grown in juvenile mice

P. Mukherjee, J. Maurer, S. A. Stopka, B. Greenwood, J. J. A. Henao, S. Karmacharya, A. Chimento, N. Ta, D. C. Lee, T. Duraj, R. T. Bronson, M. A. Kiebish, T. N. Seyfried

This study shows that combining a ketogenic diet with mebendazole or devimistat improves therapeutic outcomes in preclinical high-grade glioma models in juvenile mice.

bioRxiv · Jun 9, 2023 · PreprintCancer Biology