Author

C. Cioffi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

C. S. Bakshi· 1 shared G. T. Montelione· 1 shared K. King· 1 shared L. Mazzei· 1 shared M. Alqahtani· 1 shared M. Malik· 1 shared M. Worden· 1 shared P. Muthuraman· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

C. S. Bakshi

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2 papers

Recent·Most cited

An isothermal calorimetry assay for determining steady state kinetic and enzyme inhibition parameters for SARS-CoV-2 3CL-protease

L. Mazzei, S. Ranieri, R. Greene-Cramer, C. Cioffi, G. T. Montelione, S. Ciurli

This paper develops an ITC assay to measure kinetic and inhibition parameters of SARS-CoV-2 3CL-protease, revealing two inhibition modes and deriving kinetic constants with high precision.

bioRxiv · Jan 31, 2024 · PreprintBiochemistry

Stringent Response Governs the Virulence and Oxidative Stress Resistance of Francisella tularensis

Z. Ma, K. King, M. Alqahtani, M. Worden, P. Muthuraman, C. Cioffi, C. S. Bakshi, M. Malik

This study shows that the stringent response in Francisella tularensis enhances oxidative stress resistance by altering gene expression and increasing antioxidant enzyme production.

bioRxiv · May 31, 2019Microbiology