Targeting BDCA2 suppresses Plasmacytoid dendritic cell dependent interferon response and tissue fibrosis
R. L. Ross, C. Corinaldesi, G. Migneco, I. Carr, A. Antanaviciute, A. Carriero, C. Wasson, I. Georgiou, J. H. W. Distler, S. Holmes, Y. M. El-Sherbiny, C. S. McKimmie, F. Del Galdo
This study shows that targeting BDCA2 reduces pDC-driven interferon responses and fibrosis in preclinical models of skin inflammation.
bioRxiv · Jan 30, 2020 · PreprintImmunology