M. Hirai

Exact centriole counts are critical for B cell development but not function

The paper shows that precise centriole counts are essential for B cell development but not for immune function.

A combination of two-enzyme system and enzyme engineering improved the activity of a new PET hydrolase identified from soil bacterial genome

The paper identifies a novel PET hydrolase from soil bacteria, enhances its activity with CALB and protein engineering, achieving 95.5% PET degradation.

Distinct groups of RNA viruses associated with thermoacidophilic bacteria

The paper identifies two new groups of RNA viruses associated with thermoacidophilic bacteria in acidic hot springs and other environments.

Diverse DNA modification in marine prokaryotic and viral communities

The paper identifies diverse DNA modifications in marine prokaryotic and viral communities using metaepigenomic analysis and reveals novel MTase-motif pairs and conserved motifs in Alphaproteobacteria.

Emergence of artemisinin-resistant Plasmodium falciparum with kelch13 C580Y mutations on the island of New Guinea

The paper identifies the emergence of artemisinin-resistant Plasmodium falciparum with kelch13 C580Y mutations in Papua New Guinea and suggests an independent origin with distinct genetic features.

Genomes of Thaumarchaeota from deep sea sediments reveal specific adaptations of three independently evolved lineages

The paper presents 11 metagenome-assembled genomes of ammonia oxidizing archaea from marine sediments, revealing three independently evolved lineages with specific adaptations to deep-sea conditions.

Microbial community and geochemical analyses of trans-trench sediments for understanding the roles of hadal environments

The paper analyzes microbial communities and geochemistry in hadal trench sediments to understand microbial distribution and ecological drivers.

Bottleneck Size-Dependent Changes in the Genetic Diversity and Specific Growth Rate of a Rotavirus A Strain

This study examines how different bottleneck sizes affect genetic diversity and growth rate in a rotavirus A strain during serial passage, finding increased diversity and growth rate under stronger bottlenecks.

Direct Evidence of Effect of Glycerol on Hydration and Helix-to-Sheet Transition of Myoglobin

This paper investigates glycerol's effect on myoglobin's hydration and structural transitions using scattering techniques, showing preservation of hydration shells at low concentrations and structural stabilization at higher concentrations.