Luminal transport rates through intact endoplasmic reticulum limit the magnitude of localized Ca2+ signals
C. Crapart, Z. C. Scott, T. Konno, A. Sharma, P. Parutto, D. M. Bailey, L. M. Westrate, E. Avezov, E. F. Koslover
The paper shows that ER shape affects Ca2+ release efficiency through transport limitations and buffer protein mobility.
bioRxiv · Jun 23, 2023Cell Biology