Author

T. Konno

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Assay:imaging· 3 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

E. Avezov· 4 shared C. Crapart· 2 shared C. F. Kaminski· 2 shared G. S. Kaminski Schierle· 2 shared P. Parutto· 2 shared A. A. Lapkin· 1 shared A. Agrawal· 1 shared A. Brown· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersCell Biology

E. Avezov

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Luminal transport rates through intact endoplasmic reticulum limit the magnitude of localized Ca2+ signals

C. Crapart, Z. C. Scott, T. Konno, A. Sharma, P. Parutto, D. M. Bailey, L. M. Westrate, E. Avezov, E. F. Koslover

The paper shows that ER shape affects Ca2+ release efficiency through transport limitations and buffer protein mobility.

bioRxiv · Jun 23, 2023Cell Biology

ERnet: a tool for the semantic segmentation and quantitative analysis of endoplasmic reticulum topology for video-rate super-resolution imaging

M. Lu, C. N. Christensen, J. M. Weber, T. Konno, N. F. Laubli, K. M. Scherer, E. Avezov, P. Lio, A. A. Lapkin, G. S. Kaminski Schierle, C. F. Kaminski

ERnet quantifies ER topology dynamics using video-rate super-resolution imaging and semantic segmentation, enabling analysis of ER morphology changes in response to genetic or metabolic perturbations.

bioRxiv · May 17, 2022 · PreprintBioengineering

Intracellular Aβ42 aggregation leads to cellular thermogenesis

C. W. Chung, A. D. Stephens, T. Konno, E. Ward, E. Avezov, C. F. Kaminski, A. Hassanali, G. S. Kaminski Schierle

This paper shows that Aβ42 aggregation in live cells increases intracellular temperature, which can be mitigated by aggregation inhibitors and is independent of mitochondrial damage.

bioRxiv · Mar 30, 2022Biophysics

Endoplasmic Reticulum morphological regulation by RTN4/NOGO modulates neuronal regeneration by slowing luminal transport

T. Konno, P. Parutto, D. M. D. Bailey, V. Davi, C. Crapart, M. A. Awadelkareem, C. Hockings, A. Brown, K. M. Xiang, A. Agrawal, J. E. Chambers, M. V. Werp, K. Koning, E. Metzakopian, L. Westrate, , E. Avezov

The paper shows RTN4/NOGO regulates ER morphology, which modulates luminal transport and Ca2+ delivery, affecting axonogenesis in neurons.

bioRxiv · May 10, 2021Cell Biology