P. Parutto

Luminal transport rates through intact endoplasmic reticulum limit the magnitude of localized Ca2+ signals

The paper shows that ER shape affects Ca2+ release efficiency through transport limitations and buffer protein mobility.

High-throughput super-resolution single particle trajectory analysis reconstructs organelle dynamics and membrane re-organization

This paper introduces a computational method to analyze high-throughput super-resolution single-particle trajectories, enabling reconstruction of organelle dynamics and membrane reorganization.

Endoplasmic Reticulum morphological regulation by RTN4/NOGO modulates neuronal regeneration by slowing luminal transport

The paper shows RTN4/NOGO regulates ER morphology, which modulates luminal transport and Ca2+ delivery, affecting axonogenesis in neurons.

The structure and global distribution of the endoplasmic reticulum network is actively regulated by lysosomes

This study shows lysosomes actively regulate ER remodeling by repositioning, affecting ER tubule distribution and morphology in response to metabolic changes.

Reconstructing wells from high density regions extracted from super-resolution single particle trajectories

The paper develops statistical methods to reconstruct potential wells from super-resolution single particle trajectories, applying them to analyze voltage-gated calcium channels and phospholipids on neuronal cells.