Author

C. D. Hyland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. J. Kueh· 1 shared A. P. Ng· 1 shared C. C. Bell· 1 shared D. M. Tarlinton· 1 shared E. Leong· 1 shared E. Viney· 1 shared G. M. Bidgood· 1 shared G. Smyth· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. J. Kueh

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2 papers

Recent·Most cited

CD45 limits Natural Killer cell development from common lymphoid progenitors

L. G. Meza Guzman, C. D. Hyland, G. M. Bidgood, E. Leong, Z. Shen, W. Goh, T. Kratina, J. Rautela, J. Vince, S. Nicholson, N. Huntington

This study shows that CD45 deficiency in common lymphoid progenitors causes NK cell developmental defects, not enhanced persistence, suggesting CD45 inhibition could improve in vitro NK cell generation for therapy.

bioRxiv · Apr 17, 2023 · PreprintCell Biology

An Erg driven transcriptional program controls B-lymphopoiesis

A. P. Ng, H. D. Coughlan, S. Hediyeh-zadeh, K. Behrens, T. M. Johanson, M. S. Y. Low, C. C. Bell, O. Gilan, Y.-C. Chan, A. J. Kueh, T. Boudier, L. DiRago, C. D. Hyland, H. Ierino, S. Mifsud, , W. S. Alexander

This study identifies Erg as a critical transcription factor initiating B-lymphopoiesis by regulating gene networks essential for B-cell development and V(D)J recombination.

bioRxiv · Dec 3, 2019 · PreprintImmunology