Author

A. P. Ng

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:clustering· 2 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

J. Schreuder· 2 shared S. L. Nutt· 2 shared T. S. Weber· 2 shared W. S. Alexander· 2 shared A. Baldi· 1 shared A. J. Kueh· 1 shared A. Jacobsen· 1 shared A. L. Garnham· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersImmunology

J. Schreuder

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A multi-track landscape of haematopoiesis informed by cellular barcoding and agent-based modelling

D. Lin, S. Zhang, J. Schreuder, J. Tran, D. Metcalf, T. Sargeant, A. P. Ng, T. S. Weber, S. Naik

This study uses cellular barcoding and agent-based modeling to reveal clonal fate patterns in hematopoiesis, showing that stem and progenitor cells are often less multipotent than previously thought.

bioRxiv · Mar 28, 2024 · PreprintImmunology

A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation

S. E. Garnish, K. R. Martin, M. Kauppi, V. Jackson, R. Ambrose, V. V. Eng, S. Chiou, Y. Meng, D. Frank, E. C. Tovey Crutchfield, K. M. Patel, A. Jacobsen, G. Atkin-Smith, L. Di Rago, M. Doerflinger, , J. Hildebrand

The paper shows that a common MLKL polymorphism, S132P, enhances necroptotic activity in human cells and impairs recovery from infection in mice.

bioRxiv · Sep 8, 2022 · PreprintImmunology

Iron homeostasis governs erythroid phenotype in Polycythemia Vera

C. Bennett, V. E. Jackson, A. Pettikiriarachchi, T. Hayman, U. Schaeper, G. Moir-Meyer, K. Fielding, R. Ataide, D. Clucas, A. Baldi, A. L. Garnham, C. S. Li-Wai-Suen, W. S. Alexander, M. Bahlo, K. Burbury, , S.-R. Pasricha

This study links iron homeostasis to Polycythemia Vera by showing HFE mutations affect hepcidin expression, which regulates erythroid phenotype.

bioRxiv · May 3, 2022 · PreprintCancer Biology

The clonal and molecular aetiology of emergency dendritic cell development

D. S. Lin, L. Tian, S. Tomei, D. Amann-Zalcenstein, T. M. Baldwin, T. S. Weber, J. Schreuder, O. Stonehouse, J. Rautela, N. D. Huntington, A. P. Ng, S. L. Nutt, S. Taoudi, M. E. Ritchie, P. D. Hodgkin, S. H. Naik

This study investigates Flt3L-driven emergency dendritic cell development, revealing clonal expansion and molecular mechanisms in HSPCs leading to cDC1 generation.

bioRxiv · May 28, 2020 · PreprintImmunology

An Erg driven transcriptional program controls B-lymphopoiesis

A. P. Ng, H. D. Coughlan, S. Hediyeh-zadeh, K. Behrens, T. M. Johanson, M. S. Y. Low, C. C. Bell, O. Gilan, Y.-C. Chan, A. J. Kueh, T. Boudier, L. DiRago, C. D. Hyland, H. Ierino, S. Mifsud, , W. S. Alexander

This study identifies Erg as a critical transcription factor initiating B-lymphopoiesis by regulating gene networks essential for B-cell development and V(D)J recombination.

bioRxiv · Dec 3, 2019 · PreprintImmunology