Author

C. Di Germanio

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:spatial domain detection· 2 Research Focus:clustering· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

G. Simmons· 3 shared M. P. Busch· 3 shared M. Stone· 3 shared A. Jain· 2 shared P. L. Felgner· 2 shared R. Ramiro De Assis· 2 shared A. A. Ardeshir· 1 shared A. Jasinskas· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersImmunology

G. Simmons

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Author profile →

3 papers

Recent·Most cited

Administration of vaccine-boosted COVID-19 convalescent plasma to SARS-CoV-2 infected hamsters decreases virus replication in lungs and hastens resolution of the infection despite transiently enhancing disease and lung pathology.

T. Carroll, T. Wong, M. K. Morris, C. Di Germanio, Z.-M. Ma, M. Stone, E. E. Ball, L. Fritts, A. Rustagi, G. Simmons, M. P. Busch, C. J. Miller

This study shows that vaccine-boosted convalescent plasma reduces SARS-CoV-2 replication in hamsters but temporarily worsens disease and lung pathology.

bioRxiv · Aug 22, 2023 · PreprintImmunology

Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity reduces lung inflammation

K. K. A. Van Rompay, K. J. Olstad, R. L. Sammak, J. Dutra, J. K. Watanabe, J. L. Usachenko, R. Immareddy, J. W. Roh, A. Verma, Y. Shaan Lakshmanappa, B. Schmidt, C. Di Germanio, N. Rizvi, M. Stone, G. Simmons, , J. R. Reader

This study treats SARS-CoV-2 infected macaques with high-titer convalescent plasma, showing reduced lung inflammation without affecting virus replication.

bioRxiv · Sep 1, 2021 · PreprintImmunology

Distinct SARS-CoV-2 Antibody Reactivity Patterns in Coronavirus Convalescent Plasma Revealed by a Coronavirus Antigen Microarray

R. Ramiro de Assis, A. Jain, R. Nakajima, A. Jasinskas, S. Khan, L. J. Dumont, K. Kelly, G. Simmons, M. Stone, C. Di Germanio, M. P. Busch, P. L. Felgner

This study uses a coronavirus antigen microarray to identify distinct antibody reactivity patterns in SARS-CoV-2 convalescent plasma, showing high concordance with existing assays and revealing clusters with potential implications for treatment efficacy.

bioRxiv · Sep 16, 2020Immunology