Author

Y. Shaan Lakshmanappa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:rat· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

J. R. Reader· 2 shared J. W. Roh· 2 shared K. J. Olstad· 2 shared K. K. A. Van Rompay· 2 shared R. E. Pollard· 2 shared R. Immareddy· 2 shared R. L. Sammak· 2 shared S. S. Iyer· 2 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

J. R. Reader

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Distinct upper airway epithelium interferon-stimulated and profibrotic gene expression between adult and infant rhesus macaques infected with SARS-CoV-2

S. N. Langel, C. Garrido, C. Phan, T. Travieso, T. DeMarco, Z.-M. Ma, J. R. Reader, K. J. Olstad, R. L. Sammak, Y. Shaan Lakshmanappa, J. W. Roh, J. Watanabe, J. Usachenko, R. Immareddy, R. E. Pollard, , M. Blasi

This study compares SARS-CoV-2 infection effects in adult and infant rhesus macaques, finding distinct interferon-stimulated and profibrotic gene expression patterns in upper airway epithelium.

bioRxiv · Feb 12, 2022Immunology

Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity reduces lung inflammation

K. K. A. Van Rompay, K. J. Olstad, R. L. Sammak, J. Dutra, J. K. Watanabe, J. L. Usachenko, R. Immareddy, J. W. Roh, A. Verma, Y. Shaan Lakshmanappa, B. Schmidt, C. Di Germanio, N. Rizvi, M. Stone, G. Simmons, , J. R. Reader

This study treats SARS-CoV-2 infected macaques with high-titer convalescent plasma, showing reduced lung inflammation without affecting virus replication.

bioRxiv · Sep 1, 2021 · PreprintImmunology