Endothelial FABP4 constitutes the majority of basal circulating hormone levels and regulates lipolysis-driven insulin secretion
K. E. Inouye, K. J. Prentice, A. Lee, C. Dominguez-Gonzalez, M. X. Chen, G. Y. Lee, G. S. Hotamisligil
This study identifies endothelial cells as the main source of baseline circulating FABP4 and shows they are required for lipolysis-driven insulin secretion.
bioRxiv · Oct 13, 2022 · PreprintPhysiology