Author

C. E. Hernandez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

L. H. Hoeppner· 2 shared L. Wang· 2 shared S. K. Alam· 2 shared A. C. Cockcroft· 1 shared A. C. Roden· 1 shared B. S. Green· 1 shared C. B. Canales-Aguirre· 1 shared C. Nunes Soares Silva· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCancer Biology

L. H. Hoeppner

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

DARPP-32 promotes ERBB3-mediated resistance to molecular targeted therapy in EGFR-mutated lung adenocarcinoma

S. K. Alam, Y. Zhang, L. Wang, Z. Zhu, C. E. Hernandez, Y. Zhou, N. Yang, J. Lei, X. Chen, L. Zeng, M. A. Klein, L. H. Hoeppner

This study identifies DARPP-32 as a mediator of ERBB3-driven resistance to EGFR TKIs in lung adenocarcinoma, showing its role in promoting oncogenic signaling and tumor progression.

bioRxiv · Feb 12, 2021Cancer Biology

Shrinking of fish under warmer temperatures decrease dispersal abilities and speciation rates

J. Avaria-Llautureo, C. Venditti, M. M. Rivadeneira, O. Inonstroza-Michael, R. J. Rivera, C. E. Hernandez, C. B. Canales-Aguirre

This study shows that smaller fish in warmer waters move less and speciate less, suggesting global warming may reduce biodiversity by promoting smaller, less mobile fish.

bioRxiv · Oct 27, 2020 · PreprintEvolutionary Biology

Global drivers of diversification in a marine species complex

C. Nunes Soares Silva, N. P. Murphy, J. J. B. J. Bell, B. S. Green, G. Duhamel, A. C. Cockcroft, C. E. Hernandez, J. M. Strugnell

This study examines genome-wide divergence and introgression in rock lobster species, showing environmental and demographic factors drive speciation in a marine genus with long larval dispersal.

bioRxiv · Dec 13, 2019 · PreprintEvolutionary Biology

ASCL1-regulated DARPP-32 and t-DARPP stimulate small cell lung cancer growth and neuroendocrine tumor cell survival

S. K. Alam, L. Wang, Y. Ren, C. E. Hernandez, F. Kosari, A. C. Roden, R. Yang, L. H. Hoeppner

The paper shows that ASCL1-regulated DARPP-32 and t-DARPP promote SCLC growth and survival through Akt/Erk signaling and anti-apoptotic pathways, with t-DARPP overexpression linked to Notch signaling activation in SCLC patients.

bioRxiv · Jul 16, 2019Cancer Biology