Author

C. G. Acevedo-Rocha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1

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Research Focus:protein folding & dynamics· 2 Approach:deep learning· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

S. Osuna· 2 shared A. Bar-Even· 1 shared A. Li· 1 shared C. Calvo-Tusell· 1 shared G. M. M. Stoffel· 1 shared J. Sanchis Martinez· 1 shared L. Calzadiaz Ramirez· 1 shared L. D'Amore· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersEvolutionary Biology

S. Osuna

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2 papers

Recent·Most cited

Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics

C. G. Acevedo-Rocha, A. Li, L. D'Amore, S. Hoebenreich, J. Sanchis Martinez, P. Lubrano, M. Ferla, M. Garcia Borras, S. Osuna, M. T. Reetz

The paper quantifies cooperative mutational effects on multiple catalytic traits of a cytochrome P450 enzyme using computational methods and simulations, showing their modulation by long-range conformational dynamics.

bioRxiv · Apr 14, 2020Evolutionary Biology

In vivo selection for formate dehydrogenases with high efficiency and specificity towards NADP+

L. Calzadiaz Ramirez, C. Calvo-Tusell, G. M. M. Stoffel, S. Lindner, S. Osuna, T. J. Erb, M. Garcia-Borras, A. Bar-Even, C. G. Acevedo-Rocha

This study uses in vivo selection to engineer formate dehydrogenases with high efficiency and specificity for NADP+ regeneration.

bioRxiv · Apr 2, 2020 · PreprintBiochemistry