Author

P. Lubrano

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

H. Link· 2 shared T. Glatter· 2 shared A. Alvarado· 1 shared A. Li· 1 shared A. Stadelmann· 1 shared C. G. Acevedo-Rocha· 1 shared E. Lorenz· 1 shared G. Angelidou· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMicrobiology

H. Link

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The SPFH complex HflK-HflC regulates aerobic respiration in bacteria

M. I. Perez-Lopez, P. Lubrano, G. Angelidou, T. Glatter, N. Paczia, H. Link, V. Sourjik

This study identifies the HflK-HflC complex as essential for aerobic respiration in E. coli by regulating IspG abundance and ubiquinone levels.

bioRxiv · Apr 21, 2024Microbiology

Purine nucleotide limitation undermines antibiotic action in clinical Escherichia coli

P. Lubrano, T. Schramm, E. Lorenz, A. Alvarado, S. C. Eigenmann, A. Stadelmann, S. Thavapalan, N. Waffenschmidt, T. Glatter, S. Peter, K. Drescher, H. Link

This study identifies purine nucleotide limitation as a mechanism conferring antibiotic resistance in E. coli by reducing ATP supply and upregulating the purine nucleoside transporter PunC.

bioRxiv · Jun 22, 2023 · PreprintMicrobiology

Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics

C. G. Acevedo-Rocha, A. Li, L. D'Amore, S. Hoebenreich, J. Sanchis Martinez, P. Lubrano, M. Ferla, M. Garcia Borras, S. Osuna, M. T. Reetz

The paper quantifies cooperative mutational effects on multiple catalytic traits of a cytochrome P450 enzyme using computational methods and simulations, showing their modulation by long-range conformational dynamics.

bioRxiv · Apr 14, 2020Evolutionary Biology