Author

C. G. K. Ziegler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Assay:scRNA-seq· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. K. Shalek· 3 shared J. Ordovas-Montanes· 3 shared A. H. Owings· 1 shared A. Moodley· 1 shared A. Parker· 1 shared A. W. Navia· 1 shared B. D. Walker· 1 shared B. H. Horwitz· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersImmunology

A. K. Shalek

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3 papers

Recent·Most cited

ImmunologybioRxivFeb 20, 2021

Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19

C. G. K. Ziegler, V. N. Miao, A. H. Owings…·J. Ordovas-Montanes

This study analyzes nasopharyngeal samples from COVID-19 patients and healthy controls to identify how SARS-CoV-2 infection affects respiratory epithelial cells and immune responses, finding impaired local intrinsic immunity in severe cases.

DOI 10.1016/j.cell.2021.07.023

humanscRNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintNov 11, 2019

Sensory Neurons Innervate Peripheral Lymph Nodes and Locally Regulate Gene Expression in Postsynaptic Endothelium, Stromal Cells, and Innate Leukocytes

S. Huang, C. G. K. Ziegler, J. Austin…·U. H. von Andrian

The paper identifies sensory neurons innervating lymph nodes and shows they modulate gene expression in endothelium, stromal cells, and innate leukocytes through direct communication.

DOI 10.1101/833509

mousescRNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintMay 30, 2019

Integrated Single-Cell Analysis of Multicellular Immune Dynamics during Hyper-Acute HIV-1 Infection

S. W. Kazer, T. P. Aicher, D. M. Muema…·A. K. Shalek

The paper uses single-cell RNA-sequencing to study immune dynamics in HIV-1 infection, identifying key cellular responses and their temporal progression in untreated individuals.

DOI 10.1101/654814

humanscRNA-seq

𝕏 PostBluesky