Author

B. H. Horwitz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Y. Tang· 3 shared B. Bao· 2 shared I. Patik· 2 shared S. Snapper· 2 shared A. Eran· 1 shared A. H. Owings· 1 shared A. K. Shalek· 1 shared A. Nandy· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersImmunology

Y. Tang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Bacterial Sphingolipids Exacerbate Colitis by Inhibiting ILC3-derived IL-22 Production.

B. Bao, Y. Wang, P. Boudreau, X. Song, M. Wu, X. Chen, I. Patik, Y. Tang, J. D. Ouahed, A. Ringel, J. Barends, C. Wu, E. P. Balskus, J. R. Thiagarajah, J. Liu, , S. Snapper

This study shows that bacterial sphingolipids worsen colitis by reducing IL-22 production from ILC3 cells in mice.

bioRxiv · Sep 5, 2023Immunology

IL-10 inhibits STAT1-dependent macrophage accumulation during microbiota-induced colitis

I. Patik, N. S. Redhu, A. Eran, B. Bao, A. Nandy, Y. Tang, S. El Sayed, Z. Shen, J. Glickman, J. G. Fox, S. Snapper, B. H. Horwitz

The paper shows IL-10R inhibits STAT1-dependent macrophage accumulation in colitis by preventing a cell-extrinsic signal, not directly affecting STAT1 function.

Mucosal Immunology · Jun 1, 2023Peer-reviewedImmunology

Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19

C. G. K. Ziegler, V. N. Miao, A. H. Owings, A. W. Navia, Y. Tang, J. D. Bromley, P. Lotfy, M. Sloan, H. Laird, H. B. Williams, M. George, R. S. Drake, T. Christian, A. Parker, C. B. Sindel, , J. Ordovas-Montanes

This study analyzes nasopharyngeal samples from COVID-19 patients and healthy controls to identify how SARS-CoV-2 infection affects respiratory epithelial cells and immune responses, finding impaired local intrinsic immunity in severe cases.

bioRxiv · Feb 20, 2021Immunology